The Baptist Church in Sturbridge was organized about 1750 and early on met in a school house, enlarged and converted into a house of worship. A new meetinghouse was erected in 1784. These first two structures were located on Fiske Hill. As described in An Historical Sketch of Sturbridge, Mass. (1838), by Joseph S. Clark, by 1832:

Their first Meetinghouse, by this time was going to decay; and as it stood at an inconvenient distance from many of the Society, in 1832 they erected a new and far more commodious one, in the centre village, on a corner of the old Burying-ground. It was dedicated Jan. 8, 1833, […] The Baptist Society have just completed [1838] the removal of their Meetinghouse to Fiskdale village, about 2 miles from its former location. As this arrangement brings the Sanctuary to the doors of many who have hitherto found it inconvenient to attend Church statedly it is presumed that they will hereafter avail themselves of that privilege.

As mentioned in the 1844 book, History of the Baptist Churches Composing the Sturbridge Association,

During the present year, (1842,) the house, having been struck with lightning, and injured to a considerable extent, has undergone a thorough repair, at an expense of about $300.

In 1947, when the Sturbridge Baptist Society was joining with another denomination, it agreed to give the meetinghouse to Old Sturbridge Village in exchange for an organ in their new church. The 1832 structure was then moved to the Village, where it is referred to as the Center Meetinghouse.